Flutamide-Induced Regression of Angiofibroma

Flutamide-induced hepatotoxicity

Abstract. – OBJECTIVE: Flutamide (FLU) is a non-steroidal antiandrogen drug approved for the treatment of advanced prostate cancer. While this indication limits the use to male patients, FLU is widely prescribed to women, off-label, for the treatment of polycystic ovary syndrome (POCS) related hirsutism and acne. According to the literature, its assumption is associated with a higher incidence ...

Metabolite profiles of flutamide in serum from patients with flutamide-induced hepatic dysfunction.

Hepatic dysfunction due to flutamide administration has been reported and this side effect often limits the use of the agent. The prediction of flutamide-induced hepatotoxicity is attributed to the proper use of the antiandrogen. In this study, we investigated whether hepatic dysfunction could be assessed by the metabolite profile in serum from patients receiving this drug. Serum samples were o...

flutamide-induced hepatotoxicity: a case report

flutamide is a non-steroidal antiandrogen commonly used in the treatment of prostate cancer. severe hepatotoxicity occurs in few patients, yet may be fatal. to date, none of the reported cases of flutamide hepatotoxicity has demonstrated thrombocytopenia and chronic liver disease. we report the case of a 55-year-old male with prostatic adenocarcinoma who developed liver failure after six months...

Middle turbinate angiofibroma: an unusual location for juvenile angiofibroma Angiofibroma de concha média: uma localização rara de angiofibroma juvenil

Os angiofibromas são os tumores vasculares histologicamente benignos mais frequentemente encontrados, com potencial destrutivo local, geralmente originários da parede lateral posterior da nasofaringe. Essas neoplasias são mais comumente observadas em adolescentes do sexo masculino e raramente são encontradas depois dos 25 anos. Raramente os angiofibromas se situam em locais extranasofaríngeos, ...

Retropharyngeal angiofibroma.